![]() ![]() Radiation force of an arbitrary acoustic beam on an elastic sphere in a fluid. Acoustic radiation force on a compressible cylinder in a standing wave. Acoustic radiation pressure on a compressible sphere. On the acoustic radiation pressure on spheres. Tensors in Mechanics and Elasticity (Academic, 1964). Axial radiation force of a Bessel beam on a sphere and direction reversal of the force. From acoustic radiation pressure to three-dimensional acoustic radiation forces. Axial radiation force exerted by general non-diffracting beams. The theory of steady forces caused by sound waves. This review paper provides an introduction to the various applications of acoustic tweezer technologies in the life sciences. Forthcoming Lab on a Chip tutorial series on acoustofluidics: acoustofluidics-exploiting ultrasonic standing wave forces and acoustic streaming in microfluidic systems for cell and particle manipulation. This comprehensive review article provides a thorough overview of the underlying physics of acoustofluidic technologies, with a particular emphasis placed on wave generation and propagation in solids and fluids.īruus, H. Microscale acoustofluidics: microfluidics driven via acoustics and ultrasonics. Finally, we provide our perspective on how to optimize device performance and discuss areas of future development.įriend, J. We also discuss data reproducibility and the need to establish standards for the deposition of data sets within the field. In addition, we review typical types of data that are obtained from acoustofluidic experiments and describe how to model different forces acting on particles within an acoustofluidic device. The experimental set-ups for each type of acoustofluidic device are discussed along with their advantages and limitations. We aim to demystify the rapidly growing field of acoustofluidics and provide a unified perspective that will allow end users to choose the acoustofluidic technology that is best suited for their research needs. In this Primer, we explain the underlying physical principles governing the design and operation of acoustofluidic technologies and describe the various implementations that have been developed for biomedical applications. Over the past decade, acoustofluidic technologies have enabled new capabilities in biomedical applications ranging from the precise patterning of heterogeneous cells for tissue engineering to the automated isolation of extracellular vesicles from biofluids for rapid, point-of-care diagnostics. Acoustofluidic technologies utilize acoustic waves to manipulate fluids and particles within fluids, all in a contact-free and biocompatible manner. ![]()
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